Publications

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Design, synthesis, and antibacterial efficacy of new methylene disalicylic acid/1,3,4-oxadiazole hybrids as dual inhibitors of DNA gyrase and topoisomerase IV

Molecular Diversity | Vol. 2 | Issue -- | 2026

DOI: https://doi.org/10.1007/s11030-026-11490-w

Computational identification of Cucurbitacin S and Kammogenin as bioactive focal adhesion kinase 2 inhibitors for targeted cancer therapy

Molecular Diversity | 2025

DOI: https://doi.org/10.1007/s11030-025-11413-1

Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties

Frontiers in Chemistry | Vol. 13 | Issue 5 | 2025

DOI: https://doi.org/10.3389/fchem.2025.1595997

Design, synthesis, antimalarial activity, and in-silico studies of new benzimidazole/pyridine hybrids as dihydrofolate reductase inhibitors

Bioorganic Chemistry | Vol. 156 | Issue 108171 | 2025

DOI: https://doi.org/10.1016/j.bioorg.2025.108171

New pyrrolidine-carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors

Chemical Biology & Drug Design | 2024

DOI: https://doi.org/10.1111/cbdd.14422

Design, synthesis, and biological evaluation of indole-2-carboxamides as SARS CoV-2 main protease inhibitors

Tetrahedron | Vol. 145 | 2023

DOI: https://doi.org/10.1016/j.tet.2023.133628

Design, synthesis and antimicrobial activity of novel quinoline-2-one hybrids as promising DNA gyrase and topoisomerase IV inhibitors

Journal of Molecular Structure | Vol. 1278 | 2023

DOI: https://doi.org/10.1016/j.molstruc.2023.134902

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Bioorganic Chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105616

Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease

Bioorganic Chemistry | 2021

DOI: https://doi.org/10.1016/j.bioorg.2021.105363

Novel 1,5-diaryl pyrazole-3-carboxamides asNovel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/ sEH inhibitors with analgesic, anti-in?ammatory, and lower cardiotoxicity effects selective COX-2/sEH inhibitors with analgesic, anti-in?ammatory, and lower cardiotoxicity effects

Bioorganic Chemistry | 2021

DOI: https://doi.org/10.1016/j.bioorg.2021.105302

Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxmide scaffold with apoptotic antiproliferative activity

Bioorganic Chemistry | 2021

DOI: https://doi.org/10.1016/j.bioorg.2021.104960