Publications

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Assembling of phenyl substituted halogens in the C3-position of substituted isatins by mono wave assisted synthesis: development of a new class of monoamine oxidase inhibitors.

Journal of computer aided molecular design | Vol. 39 | Issue 1 | 2025

DOI: https://doi.org/10.1007/s10822-025-00663-8

New class of thio/semicarbazide￾based benzyloxy derivatives as selective class of monoamine oxidase-B inhibitors

Scientific reports | Vol. 14 | Issue 31292 | 2024

DOI: https://doi.org/10.1038/s41598-024-82771-3

Recent progress in synthetic and natural COMT inhibitors for neurological disorders

ACS Omega | Vol. 9 | Issue 44 | 2024

DOI: https://doi.org/10.1021/acsomega.4c06190

A comprehensive Review of the molecular dynamics, study of chalcones,coumarins,and chromes as selective MAO-B inhibitor

Chemistry select | Vol. 9 | Issue e20240170 | 2024

DOI: https://doi.org/10.1002/slct.202401709

Targeting GABA receptors with chalcone derivative compounds, what is the evidence?

EXPERT OPINION ON THERAPEUTIC TARGETS | 2024

DOI: https://doi.org/10.1080/14728222.2023.2293752

Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents

journal of enzyme inhibition and medicinal chemistry | Vol. 38 | Issue 1 | 2023

DOI: https://doi.org/10.1080/14756366.2022.2162511

Anti-inflammatory effect of 3-fluorophenyl pyrimidinylimidazo[2,1-b]thiazole derivatives as p38α inhibitors

bioorganic chemistry | Vol. 139 | Issue - | 2023

DOI: https://doi.org/10.1016/j.bioorg.2023.106716

Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation

journal of bimolecular structure and dynamics | Vol. 42 | Issue 18 | 2023

DOI: https://doi.org/10.1080/07391102.2023.2252088

Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study

computational biology and chemistry | Vol. 42 | Issue 18 | 2023

DOI: https://doi.org/10.1016/j.compbiolchem.2023.107899

New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study

Journal of enzyme inhibition and medicinal chemistry | Vol. 38 | Issue 1 | 2023

DOI: https://doi.org/10.1080/14756366.2023.2166036

The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations

Journal of biomolecular structure and dynamics | Vol. 41 | Issue 21 | 2023

DOI: https://doi.org/10.1080/07391102.2023.2167000

Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents

Journal of enzyme inhibition and medicinal chemistry | Vol. 38 | Issue 1 | 2023

DOI: https://doi.org/10.1080/14756366.2022.2162511

Development of bromo- and fluoro-based α, β-unsaturated ketones as highly potent MAO-B inhibitors for the treatment of Parkinson's disease

Journal of Molecular Structure | 2022

DOI: https://doi.org/10.1016/j.molstruc.2022.133545

Conjugated Dienones from Differently Substituted Cinnamaldehyde as Highly Potent Monoamine Oxidase-B Inhibitors: Synthesis, Biochemistry, and Computational Chemistry

ACS OMEGA | Vol. 7 | Issue 9 | 2022

DOI: https://doi.org/10.1021/acsomega.2c00397

Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases

mol. neurobiology,SPRINGER | Vol. 59 | Issue 1 | 2021

DOI: https://doi.org/10.1007/s12035-021-02555-y

Ameliorative effect of ethoxylated chalcone-based MAO-B inhibitor on behavioural predictors of haloperidol-induced Parkinsonism in mice: evidence of its antioxidative role against Parkinson?s diseases

Environmental Science and Pollution Research | Vol. 29 | Issue 5 | 2021

DOI: https://doi.org/10.1007/s11356-021-15955-3

Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights

Drug discovery and development therapy | Vol. 31 | Issue 15 | 2021

DOI: https://doi.org/10.2147/DDDT.S310820

Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders

Environmental Science and Pollution Research, springer | Vol. 28 | Issue - | 2021

DOI: https://doi.org/10.1007/s11356-021-13320-y

A study on the effectiveness of online teaching in pharmacy education from teacher and student perspective during the COVID-19 pandemic

PHARMACY EDUCATION | Vol. 20 | Issue 2 | 2021

DOI: https://doi.org/10.46542/pe.2020.202.297301

"Exploring the therapeutic potentials of highly selective oxygenated chalcone based MAO-B inhibitors in a haloperidol-induced murine model of Parkinson?s disease"

Neurochemical Research | Vol. 45 | Issue 11 | 2020

DOI: https://doi.org/10.1007/s11064-020-03130-y

Revisiting the blood brain barrier: A hard nut to cracking the transportation of drug molecules

Brain research bulletin | Vol. 160 | 2020

DOI: https://doi.org/10.1016/j.brainresbull.2020.03.018

Design, Synthesis, and In Vitro Cytotoxic Activity of Certain 2-[3-Phenyl-4-(pyrimidin-4-yl)-1H-pyrazol1-yl] acetamide Derivatives.

Russian Journal of organic chemistry | 2020

DOI: https://doi.org/10.1134/S1070428020030239

Design, Synthesis, and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

Drug Design, Development and Therapy | 2020

DOI: https://doi.org/10.2147/DDDT.S237957

Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool

Environmental Science and Pollution Research | Vol. 18 | Issue 6 | 2019

DOI: https://doi.org/10.1007/s11356-019-07231-2

Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work

European Journal of medicinal Chemistry | Vol. 15 | Issue 182 | 2019

DOI: https://doi.org/10.1016/j.ejmech.2019.111602

. Fe3O4 nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitor.

Archiv Der Pharmazie | Vol. 352 | Issue 1 | 2019

DOI: https://doi.org/10.1002/ardp.201800174