Publications

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Bridging the gap with amide linkers: rational design, synthesis, and multi-target evaluation of sulfonamide/acetamide-NSAID hybrids as dual COX-2/5-LOX inhibitors

FUTURE MEDICINAL CHEMISTRY | Vol. 18 | Issue 2 | 2026

DOI: https://doi.org/10.1080/17568919.2025.2605716

Comparative study of the chemical profile, cytotoxic activity, and molecular docking of Serenoa repens extract and a pharmaceutical product.

Scientific Reports | Vol. 15 | Issue 34338 | 2025

DOI: https://doi.org/10.1038/s41598-025-16758-z

Pioglitazone improves tamoxifen-induced renal injury in rat model through modulating oxidative stress, inflammation, and apoptosis signaling

Tissue and Cell | Vol. 98 | Issue 103154 | 2025

DOI: https://doi.org/10.1016/j.tice.2025.103154

Targeting the p38MAPK/STAT3/NF-κB65 pathway modulates the hepatoprotective effect of pentoxifylline against sodium valproate-induced liver injury in rats; A study based on integrating network pharmacology and experiment validation.

Tissue and Cell | Vol. 96 | Issue 102924 | 2025

DOI: https://doi.org/10.1016/j.molstruc.2024.138769

Vinpocetine Mitigates Methotrexate‐Induced Liver Injury in Rats Through Modulating Intercellular Communication

Journal of Biochemical and Molecular Toxicology | Vol. 39 | Issue 70300 | 2025

DOI: https://doi.org/10.1002/jbt.70300

Flufenamic acid‑based sulfonohydrazide and acetamide derivatives NSAI as inhibitors of multi‑targets COX‑1/COX‑2/5‑LOX: design, synthesis, in silico ADMET and binding mode studies

BMC Chemistry | Vol. 19 | Issue 271 | 2025

DOI: https://doi.org/10.1186/s13065-025-01566-3

Design, synthesis, and cytotoxic evaluation of quinazoline-based derivatives as VEGER-2 inhibitors: comparative study against EGFR kinase activity, induction of apoptosis, and molecular docking study

RSC Advances | Vol. 15 | Issue 29593 | 2025

DOI: https://doi.org/10.2147/DDDT.S490930

Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities

Journal of Chemistry | Vol. 2022 | 2024

DOI: https://doi.org/10.1155/2022/4593086

Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3H)-Ones Bearing Urea Functionality as Potential VEGFR-2 Inhibitors

Drug Design, Development and Therapy | Vol. 18 | Issue 18 | 2024

DOI: https://doi.org/10.2147/DDDT.S490930

Prominent Antidiabetic and Anticancer Investigation of Scrophularia deserti Extract: Integration of Experimental andComputational Approaches

Journal of Molecular Structure | 2024

DOI: https://doi.org/10.1016/j.molstruc.2024.138769

Improving plant adaptation to soil antimony contamination: the synergistic contribution of arbuscular mycorrhizal fungus and olive mill waste

BMC Plant Biology | 2024

DOI: https://doi.org/10.1186/s12870-024-05044-1

Urtica pilulifera leaves extract mitigates cadmium induced hepatotoxicity via modulation of antioxidants, inflammatory markers and Nrf-2 signaling in mice

Frontiers in Molecular Biosciences | Vol. 11 | 2024

DOI: https://doi.org/10.3389/fmolb.2024.1365440

Antiviral activities of olive oil apigenin and taxifolin against SARS-CoV-2 RNA-dependent RNA polymerase (RdRP): In silico, pharmacokinetic, ADMET, and in-vitro approaches

Cogent Food & Agriculture | Vol. 9 | 2023

DOI: https://doi.org/10.1080/23311932.2023.2236828

Introducing of novel class of pyrano[2,3-c]pyrazole-5- carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation

Journal of Biomolecular Structure and Dynamics (JBSD) | 2023

DOI: https://doi.org/10.1080/07391102.2023.2252088

Pioglitazone ameliorates cisplatin-induced testicular toxicity by attenuating oxidative stress and inflammation via TLR4/MyD88/NF-κB signaling pathway

Journal of Trace Elements in Medicine and Biology | Vol. 80 | Issue 127287 | 2023

DOI: https://doi.org/10.1016/j.jtemb.2023.127287

Interactive Effect of Arbuscular Mycorrhizal Fungi (AMF) and Olive Solid Waste on Wheat under Arsenite Toxicity

Plants | Vol. 12 | 2023

DOI: https://doi.org/10.3390/plants12051100

Positive Interaction of Selenium Nanoparticles and Olive Solid Waste on Vanadium-Stressed Soybean Plant

Agriculture | Vol. 13 | 2023

DOI: https://doi.org/10.3390/agriculture13020426

Chromium(VI) Toxicity and Active Tolerance Mechanisms of Wheat Plant Treated with Plant Growth-Promoting Actinobacteria and Olive Solid Waste

ACS Omega | 2023

DOI: https://doi.org/10.1021/acsomega.3c02447

Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review

Frontiers in Nutrition | Vol. 9 | 2022

DOI: https://doi.org/10.3389/fnut.2022.1008349

The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation

Metabolites | 2022

DOI: https://doi.org/10.3390/metabo12090791

Mechanisms underlying the hepatoprotective effect of silymarin on fluoxetine‑induced liver injury in rats: the implication of peroxisome proliferator–activated receptor‑gamma (PPAR‑γ)

Comparative Clinical Pathology | 2022

DOI: https://doi.org/10.1007/s00580-022-03369-7

Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF‑κB and upregulating PPAR‑γ signal

Molecular Biology Reports | 2022

DOI: https://doi.org/10.1007/s11033-022-07366-5

Musa sp. Leaves Extract Ameliorates the Hepato-Renal Toxicities Induced by Cadmium in Mice

Molecules | Vol. 27 | Issue 2 | 2022

DOI: https://doi.org/10.3390/molecules27020559

Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease

Saudi Pharmaceutical Journal | Vol. 29 | Issue 11 | 2021

DOI: https://doi.org/10.1016/j.jsps.2021.09.014

Identification of non-classical hCA XII inhibitors using combination of computational approaches for drug design and discovery

Scientific Reports | Vol. 11 | Issue 15516 | 2021

DOI: https://doi.org/10.1038/s41598-021-94809-x

Repurposing of FDA Approved Alkaloids as COVID 19 Inhibitors; In Silico Studies

Pharmacognosy Journal | Vol. 13 | Issue 1 | 2021

DOI: https://doi.org/.10.5530/pj.2021.13.16

Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: synthesis and anticancer activity

Bioorganic chemistry | Vol. 105 | Issue 104369 | 2020

DOI: https://doi.org/10.1016/j.bioorg.2020.104369

Relationship between Pre-Eclampsia, Renal Impairment and Hepatic Insufficiency among Pregnant Women in Al-Jouf Area

Journal of Pharmacy and Nutrition Sciences | Vol. 10 | Issue 295-301 | 2020

DOI: https://doi.org/10.29169/1927-5951.2020.10.05.16

Bio-Medical Studies (In Vitro) on Psidium guajava Leaves.

Plant Archives | Vol. 19 | Issue 1 | 2019

DOI: https://doi.org/10.5281/zenodo.7493098