Publications

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Identification of novel thiazolyl-1,2,3-triazole hybrids as potent VEGFR-2 inhibitors for breast cancer treatment

Journal of Molecular Structure | Vol. 1357 | Issue 145203 | 2026

DOI: https://doi.org/10.1016/j.molstruc.2025.145203

Bridging the gap with amide linkers: rational design, synthesis, and multi-target evaluation of sulfonamide/acetamide-NSAID hybrids as dual COX-2/5-LOX inhibitors

Future Medicinal Chemistry | Vol. 18 | Issue 2 | 2026

DOI: https://doi.org/10.1080/17568919.2025.2605716

Statistically optimized orodispersible film loaded with Febuxostat nanosuspension to enhance oral bioavailability

Journal of Drug Delivery Science and Technology | Vol. 117 | Issue 108021 | 2026

DOI: https://doi.org/10.1016/j.jddst.2026.108021

Thiazolidinedione-Based Dual Inhibitors of α-Amylase and Aldose Reductase: Design, In Vitro Evaluation, and In Vivo Hypoglycemic Activity

Bioorganic & Medicinal Chemistry | Vol. 135 | Issue 118569 | 2026

DOI: https://doi.org/10.1016/j.bmc.2026.118569

Discovery of 1-phenyl-1,2,3-triazole ureas as dual VEGFR-2/JNK-1 type II kinase inhibitors targeting pancreatic cancer

International Journal of Biological Macrolecules | Vol. 308 | Issue 1 | 2025

DOI: https://doi.org/10.1016/j.ijbiomac.2025.142372

Olea europaea L. cv. Nepal Leaf Extract Alleviates Dyslipidemia and Inflammation Related to Obesity in Rabbits: A Network Pharmacology Approach Revealing Effective Antihyperlipidemic Bioactive Compounds

Chemistry and Biodiversity | Vol. 202402110 | Issue 1 | 2025

DOI: https://doi.org/10.1002/cbdv.202402110

Triazole-Linked Thiazolidinedione-Benzothiazole Hybrids: Design and Biological Evaluation as AChE Inhibitors

Bioorganic Chemistry | Vol. 157 | 2025

DOI: https://doi.org/10.1016/j.bioorg.2025.108295

New phenylpiperazine-thiazolidine-2,4-dione hybrids targeting MAO inhibition: Synthesis, biological evaluation, kinetic study and in silico insights

Bioorganic and Medicinal Chemistry | Vol. 121 | 2025

DOI: https://doi.org/10.1016/j.bmc.2025.118123

Synthesis and mechanistic insights of Coumarinyl-Indolinone hybrids as potent inhibitors of Leishmania major

European Journal of Medicinal Chemistry | Vol. 288 | 2025

DOI: https://doi.org/10.1016/j.ejmech.2025.117392

Biosynthesized zinc oxide nanoparticles: Multifunctional potential applications in anticancer, antibacterial, and B. subtilis DNA gyrase docking

Green Processing and Synthesis | Vol. 14 | 2025

DOI: https://doi.org/10.1515/gps-2024-0218

Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3H)-Ones Bearing Urea Functionality as Potential VEGFR-2 Inhibitors

Drug Design, Development and Therapy | Vol. 18 | 2024

DOI: https://doi.org/10.2147/DDDT.S490930

Anti-inflammatory effect of 3-fluorophenyl pyrimidinylimidazo[2,1-b] thiazole derivatives as p38α inhibitors

bioorganic chemistry | 2023

DOI: https://doi.org/10.1016/j.bioorg.2023.106716

New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study

journal of enzyme inhibition and medicinal chemistry | 2023

DOI: https://doi.org/10.1080/14756366.2023.2166036

Wound Healing and Antioxidant Properties of Launaea procumbens Supported by Metabolomic Profiling and Molecular Docking

Antioxidants | 2022

DOI: https://doi.org/10.3390/ antiox11112258

In Vitro Anti-Proliferative, and Kinase Inhibitory Activity of Phenanthroindolizidine Alkaloids Isolated from Tylophora indica

plants | 2022

DOI: https://doi.org/ 10.3390/plants11101295

Design, synthesis, and biological evaluation of novel pyridodipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells

bioorganic chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105752

Cancer Chemopreventive Potential and Chemical Profiling of Euphorbia abyssinica Endowed with Docking Studies

ACS | 2022

DOI: https://doi.org/10.1021/acsomega.1c06148

Docking Study, Synthesis, and Anti-Inflammatory Potential of Some New Pyridopyrimidine-Derived Compounds

J Inflamm Res | 2022

DOI: https://doi.org/10.2147/JIR.S343263

Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract

molecules | 2022

DOI: https://doi.org/10.3390/ molecules27020375

Molecular Detection of Fluoroquinolone Resistance among Multidrug-, Extensively Drug-, and Pan-Drug-Resistant Campylobacter Species in Egypt

Antibiotics | 2021

DOI: https://doi.org/10.3390/ antibiotics10111342

Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery

life | 2021

DOI: https://doi.org/ 10.3390/life11101070

Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights

Drug Design, Development and Therapy | 2021

DOI: https://doi.org/10.2147/DDDT.S310820

Antiulcer Potential of Olea europea L. cv. Arbequina Leaf Extract Supported by Metabolic Profiling and Molecular Docking

Antioxidants | 2021

DOI: https://doi.org/10.3390/antiox10050644

Potential Anticancer Lipoxygenase Inhibitors from the Red Sea-Derived Brown Algae Sargassum cinereum: An In-Silico-Supported In-Vitro Study

Antibiotics | 2021

DOI: https://doi.org/10.3390/antibiotics10040416

Identification of N-phenyl-2-(phenylsulfonyl)acetamides/ propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities

European Journal of Medicinal Chemistry | 2021

DOI: https://doi.org/10.1016/j.ejmech.2021.113360

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies

European Journal of Medicinal Chemistry | 2020

DOI: https://doi.org/10.1016/j.ejmech.2020.112745