Publications

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Terpenes Encapsulated Polycaprolactone Nanoparticles for Topical Delivery of Hydrocortisone: In Vitro Study and In Vivo Appraisal

ASSAY and Drug Development Technologies | 2026

DOI: https://doi.org/10.1177/1540658X251410481

Tunable nanospanlastics for 18α-Glycyrrhetinic acid brain targeted delivery to manage cognitive deficits and misfolded protein aggregates in Alzheimer's disease: In vitro optimization and in vivo pharmacodynamics assessment

Journal of Drug Delivery Science and Technology | Vol. 116 | Issue 107959 | 2025

DOI: https://doi.org/10.1016/j.jddst.2025.107959

In-silico studies, synthesis, and pharmacological screening of novel multitarget diphenylpyrazole scaffold as EGFR/BRAF and cyclooxygenase-2 inhibitors

scientific reports | Vol. 16 | 2025

DOI: https://doi.org/10.1038/s41598-025-33006-6

Antiviral potential of Corchorus olitorius fixed oil loaded into poly(D,L-lactide-co-glycolide)/poly(ε-caprolactone) (PLGA/PCL) nanoparticles against HSV-1 virus, supported by network analysis

Scientific Reports | Vol. 15 | Issue 1 | 2025

DOI: https://doi.org/10.1038/s41598-025-15718-x

Nose-to-Brain Delivery of Armodafinil Loaded Spanlastics in Situ Gel: Formulation, Statistical Optimization, and Pharmacokinetics Evaluation

Journal of Pharmaceutical Innovation | Vol. 20 | Issue 6 | 2025

DOI: https://doi.org/10.1007/s12247-025-10159-5

Development of carboximidamide small molecule nanogels as potent antimicrobial functional drug delivery systems

RSC advances | Vol. 15 | Issue 43 | 2025

DOI: https://doi.org/10.1039/D5RA05150A

Paliperidone Acid-Based Cocrystal for Improving Biopharmaceutical Properties: In Vitro and In Vivo Evaluation

ACS omega | Vol. 10 | Issue 37 | 2025

DOI: https://doi.org/10.1021/acsomega.5c06856

Determinants of Oral Delivery from Two Lipid Nanocarriers: Systematic Review and Meta-analysis of Bioavailability Studies.

Journal of Drug Delivery Science and Technology | Vol. 111 | 2025

DOI: https://doi.org/10.1016/j.jddst.2025.107191

In Vitro and In Vivo Appraisal of Glycerylmonostearate/chitosan Hybrid Nanocapsules As Peroral Delivery System of Simvastatin

AAPS PharmSciTech | Vol. 26 | Issue 5 | 2025

DOI: https://doi.org/10.1208/s12249-025-03135-2

Crafting cationic lecithmer nanocomposites as promising wagons for brain targeting of cinnamaldehyde: Accentuated neuroprotection via downregulation of Aβ1-42/p-tau crosstalk

Journal of Drug Delivery Science and Technology | 2025

DOI: https://doi.org/10.1016/j.jddst.2025.106664

Intranasal trimethyl chitosan-coated emulsomes containing tizanidine as brain-targeted therapy in spasticity: formulation, optimization, and pharmacokinetic assessment

Drug Delivery and Translational Research | 2024

DOI: https://doi.org/10.1007/s13346-024-01753-0

Brain targeting of venlafaxine via intranasal transbilosomes thermogel for improved management of depressive disorder

Journal of Pharmaceutical Sciences | Vol. 113 | Issue 11 | 2024

DOI: https://doi.org/10.1016/j.xphs.2024.08.026

Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis

International Journal of Pharmaceutics: X | 2024

DOI: https://doi.org/10.1016/j.ijpx.2023.100225

Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges

Polymers | 2023

DOI: https://doi.org/10.3390/polym15051123

Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures

International Journal of Pharmaceutics: X | 2023

DOI: https://doi.org/10.1016/j.ijpx.2023.100206

Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: II. Antidepressant Effect in an Experimental Animal Model

Pharmaceutics | 2023

DOI: https://doi.org/10.3390/pharmaceutics15082095

Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: I. Optimization, Characterization, Brain Localization, and Cytotoxic Studies

Pharmaceutics | 2023

DOI: https://doi.org/10.3390/pharmaceutics15071805

Oral sildenafil citrate: a potential approach for improvement of endometrial thickness and treatment of unexplained infertility in women

European Review for Medical and Pharmacological Sciences | 2023

DOI: https://doi.org/10.26355/eurrev_202305_32465

Exploring the potential of quercetin/aspirin-loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced-colorectal cancer in rats

Drug Delivery and Translational Research | 2023

DOI: https://doi.org/10.1007/s13346-023-01338-3

Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation

Journal of Drug Delivery Science and Technology | 2023

DOI: https://doi.org/10.1016/j.jddst.2023.104978

Assessment of Ketamine Adult Anesthetic Doses in Pediatrics Using Pharmacokinetic Modeling and Simulations

Pharmacotherapy | 2022

DOI: https://doi.org/10.1002/phar.2243

Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis

Drug Development and Industrial Pharmacy | 2022

DOI: https://doi.org/10.1080/03639045.2020.1871005

Development, optimization, and in vitro/in vivo characterization of enhanced lipid nanoparticles for ocular delivery of ofloxacin: the influence of pegylation and chitosan coating

AAPS PharmSciTech | 2022

DOI: https://doi.org/10.1208/s12249-019-1371-6

Transfersomal nanovesicles for nose-to-brain delivery of ofloxacin for better management of bacterial meningitis: Formulation, optimization by Box-Behnken design, characterization and in vivo pharmacokinetic study

Journal of Drug Delivery Science and Technology | 2022

DOI: https://doi.org/10.1016/j.jddst.2019.101304

Development and assessment of phospholipid-based luteolin-loaded lipid nanocapsules for skin delivery

International Journal of Pharmaceutics | 2022

DOI: https://doi.org/10.1016/j.ijpharm.2022.122375

Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

Journal of Controlled Release | 2022

DOI: https://doi.org/10.1016/j.jconrel.2022.10.005

Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats

Pharmaceutics | 2022

DOI: https://doi.org/10.3390/pharmaceutics14102023

EthoLeciplex: a new tool for effective cutaneous delivery of minoxidil

Drug Development and Industrial Pharmacy | 2022

DOI: https://doi.org/10.1080/03639045.2022.2124261

New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling

Pharmaceuticals | 2022

DOI: https://doi.org/10.3390/ph15091134

Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: Improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats

Drug Delivery | 2022

DOI: https://doi.org/10.1080/10717544.2022.2110997

Rutin and Quercetin Counter Doxorubicin-Induced Liver Toxicity in Wistar Rats via Their Modulatory Effects on Inflammation, Oxidative Stress, Apoptosis, and Nrf2

Oxidative Medicine and Cellular Longevity | 2022

DOI: https://doi.org/10.1155/2022/2710607

LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from Origanum majorana as Antibacterial and Antioxidant Potentialities

Plants | 2022

DOI: https://doi.org/10.3390/plants11141871

Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation

Drug Delivery | 2022

DOI: https://doi.org/10.1080/10717544.2022.2092236

Intranasal delivery of granisetron to the brain via nanostructured cubosomes-based in situ gel for improved management of chemotherapy-induced emesis

Pharmaceutics | 2022

DOI: https://doi.org/10.3390/pharmaceutics14071374

Role of ADMA/DDAH-1 and iNOS/eNOS signaling in the gastroprotective effect of tadalafil against indomethacin-induced gastric injury

Biomedicine & Pharmacotherapy | 2022

DOI: https://doi.org/10.1016/j.biopha.2022.113026

Chitosan Silver and Gold Nanoparticle Formation Using Endophytic Fungi as Powerful Antimicrobial and Anti-Biofilm Potentialities

Antibiotics | 2022

DOI: https://doi.org/10.3390/antibiotics11050668

Impact of highly phospholipid-containing lipid nanocarriers on oral bioavailability and pharmacodynamics performance of genistein

Pharmaceutical Development and Technology | 2022

DOI: https://doi.org/10.1080/10837450.2022.2076111

Arabinoxylan-Carboxymethylcellulose Composite Films for Antibiotic Delivery to Infected Wounds

Polymers | 2022

DOI: https://doi.org/10.3390/polym14091769

Fabrication and In Vitro/In Vivo Appraisal of Metronidazole Intra-Gastric Buoyant Sustained-Release Tablets in Healthy Volunteers

Pharmaceutics | 2022

DOI: https://doi.org/10.3390/pharmaceutics14040863

Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation

Pharmaceutics | 2022

DOI: https://doi.org/10.3390/pharmaceutics14030563

Lipid nanocarriers overlaid with chitosan for brain delivery of berberine via the nasal route

Pharmaceuticals | 2022

DOI: https://doi.org/10.3390/ph15030281

Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection via Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis

Pharmaceuticals | 2021

DOI: https://doi.org/10.3390/ph14121225

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Nanomaterials | 2021

DOI: https://doi.org/10.3390/nano11112920

Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes

Pharmaceutics | 2021

DOI: https://doi.org/10.3390/pharmaceutics13081197

Antibiotic-Loaded Psyllium Husk Hemicellulose and Gelatin-Based Polymeric Films for Wound Dressing Application

Pharmaceutics | 2021

DOI: https://doi.org/10.3390/pharmaceutics13020236

Physically optimized nano-lipid carriers augment raloxifene and vitamin d oral bioavailability in healthy humans for management of osteoporosis

Journal of Pharmaceutical Sciences | 2020

DOI: https://doi.org/10.1016/j.xphs.2020.03.009

Changing the Drug Delivery System: Does it Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug

Pharmaceutics | 2020

DOI: https://doi.org/10.3390/pharmaceutics12040297

Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity

Pharmaceutics | 2020

DOI: https://doi.org/10.3390/pharmaceutics12020160

The influence of solid/solvent interfacial interactions on physicochemical and mechanical properties of ofloxacin

Journal of Pharmaceutical Innovation | 2020

DOI: https://doi.org/10.1007/s12247-020-09431-7

Quality by design (QbD) based development and validation of bioanalytical RP-HPLC method for dapagliflozin: forced degradation and preclinical pharmacokinetic study

Journal of Liquid Chromatography & Related Technologies | 2020

DOI: https://doi.org/10.1080/10826076.2019.1667820

The Pharmacokinetics of DEX in Infants and Children following Orthotopic Liver Transplantation

Anesthesia and analgesia | 2020

DOI: https://doi.org/10.1213/ANE.0000000000003761

A novel nanogel loaded with chitosan decorated bilosomes for transdermal delivery of terbutaline sulfate: artificial neural network optimization, in vitro characterization and in vivo evaluation

Drug Delivery and Translational Research | 2019

DOI: https://doi.org/10.1007/s13346-019-00688-1

Development of novel dapagliflozin loaded solid self-nanoemulsifying oral delivery system: Physiochemical characterization and in vivo antidiabetic activity

Journal of Drug Delivery Science and Technology | 2019

DOI: https://doi.org/10.1016/j.jddst.2019.101279

Antimicrobial disposition during pediatric continuous renal replacement therapy using an ex vivo model

Critical care medicine | 2019

DOI: https://doi.org/10.1097/CCM.0000000000003895