Publications
Metabolite Profiling and Skin Anti-Aging Potential of Astragalus sarcocolla: Antioxidant, Enzyme Inhibitory, and Computational Insights
Bridging the gap with amide linkers: rational design, synthesis, and multi-target evaluation of sulfonamide/acetamide-NSAID hybrids as dual COX-2/5-LOX inhibitors
Emphasizing the role of oxidative stress and Sirt-1/Nrf2 and TLR-4/NF- B in Tamarix aphylla mediated neuroprotective potential in rotenone-induced Parkinson’s disease: In silico and in vivo study
New Antiproliferative Pyrazole/Quinoline Hybrids: Design, Synthesis, and Biological Evaluation as EGFR Inhibitors
Design, synthesis, in silico studies, and antiproliferative activity of a novel series of thiazole/1,2,3-triazole hybrids as apoptosis inducers and multi-kinase inhibitors endowed with anti-breast cancer activity
Nose-to-Brain Delivery of Armodafinil Loaded Spanlastics in Situ Gel: Formulation, Statistical Optimization, and Pharmacokinetics Evaluation
Comparative study of the chemical profile, cytotoxic activity, and molecular docking of Serenoa repens extract and a pharmaceutical product.
Pioglitazone improves tamoxifen-induced renal injury in rat model through modulating oxidative stress, inflammation, and apoptosis signaling
Non-coding RNA-mediated gene regulation in Alzheimer's disease pathogenesis: molecular insights and emerging innovations
Phenolic profiling unravels the chemopreventive components of Melaleuca citrina (Curtis) Dum.Cours. fruits by integrating LC-MS/MS, in vitro studies, docking and molecular dynamic simulation
Targeting amyloid β42 aggregation using a structurally defined graphene quantum dot model: A combined molecular and biological investigation
The novel Bruton tyrosine kinase inhibitor branebrutinib abrogates lipopolysaccharide/galactosamine-induced hepatic injury via limiting inflammation and oxidative stress
The novel Bruton tyrosine kinase inhibitor branebrutinib abrogates lipopolysaccharide/galactosamine-induced hepatic injury via limiting inflammation and oxidative stress
Targeting the p38MAPK/STAT3/NF-κB65 pathway modulates the hepatoprotective effect of pentoxifylline against sodium valproate-induced liver injury in rats; A study based on integrating network pharmacology and experiment validation.
Vinpocetine Mitigates Methotrexate‐Induced Liver Injury in Rats Through Modulating Intercellular Communication
Targeting amyloid β42 aggregation using a structurally defined graphene quantum dot model: A combined molecular and biological investigation
Terpinen-4-ol Targets HIF-1α/TGF-β1/TNF-α Axis to Attenuate Ethanol-Induced Hepatotoxicity: Network Pharmacology and In Vitro Validation
Development of Lipid Polymer Hybrid Nanoparticles of Abietic Acid: Optimization, In-Vitro and Preclinical Evaluation
Flufenamic acid‑based sulfonohydrazide and acetamide derivatives NSAI as inhibitors of multi‑targets COX‑1/COX‑2/5‑LOX: design, synthesis, in silico ADMET and binding mode studies
Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies
New antiproliferative 1,3,4-oxadiazole/benzimidazole derivatives: Design, synthesis, and biological evaluation as dual EGFR and BRAFV600E inhibitors
In silico and in vivo evaluation of erucic acid against pentylenetetrazole-induced seizures in mice by modulating oxidative stress, neurotransmitters and neuroinflammation markersPen
Anti-Inflammatory, Antihyperalgesic, and Gastric Safety Profiling of Ocimene: Attenuation of Nonsteroidal Anti-Inflammatory Drug- Induced Gastric Ulcers by Modulating Toll-like Receptor 4 and Pyroptosis Pathways
Design, synthesis, and cytotoxic evaluation of quinazoline-based derivatives as VEGER-2 inhibitors: comparative study against EGFR kinase activity, induction of apoptosis, and molecular docking study
Deciphering farnesol’s anti-arthritic and immunomodulatory potential by targeting multiple pathways: a combination of network pharmacology guided exploration and experimental verification
Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities
Intranasal trimethyl chitosan-coated emulsomes containing tizanidine as brain-targeted therapy in spasticity: formulation, optimization, and pharmacokinetic assessment
Salicylalazine: A Novel Therapeutic Agent Targeting TLR4/NLRP3/GSDMD-Mediated Pyroptosis in Rheumatoid Arthritis
Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3H)-Ones Bearing Urea Functionality as Potential VEGFR-2 Inhibitors
Design and synthesis of new quinoline-ester/-amide derivatives as potent antiproliferative agent targeting EGFR and BRAFV600E kinases
Design, Synthesis and Biological Evaluation of Syn and Anti-like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action
Exploring the potential of quercetin/aspirin‑loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced‑colorectal cancer in rats
Novel 1,2,4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity
Optimization and SAR investigation of novel 2,3- dihydropyrazino[1,2-a] indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities
A superabsorbent and pH-responsive copolymer-hydrogel based on acemannan from Aloe vera (Aloe barbadensis M.): A smart material for drug delivery
Prominent Antidiabetic and Anticancer Investigation of Scrophularia deserti Extract: Integration of Experimental andComputational Approaches
Improving plant adaptation to soil antimony contamination: the synergistic contribution of arbuscular mycorrhizal fungus and olive mill waste
The role of genetic polymorphisms in the sulfation of pregnenolone by human cytosolic sulfotransferase SULT2B1a
Urtica pilulifera leaves extract mitigates cadmium induced hepatotoxicity via modulation of antioxidants, inflammatory markers and Nrf-2 signaling in mice
Design, synthesis, and biological evaluation of indole-2-carboxamides as SARS CoV-2 main protease inhibitors
Fabrication and optimization of febuxostat-loaded chitosan nanocarriers for better pharmacokinetics profile
Synthesis of bis‑thiohydantoin derivatives as an antiproliferative agents targeting EGFR inhibitory pathway
Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies
Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors
Geraniol suppresses oxidative stress, inflammation and interstitial collagenase to protect against inflammatory arthritis.
Discovery of new 5-substituted-indole-2- carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action
Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges
Synthesis and Antiproliferative Potential of Thiazole and 4- Thiazolidinone Containing Motifs as Dual Inhibitors of EGFR and BRAFV600E
Antiviral activities of olive oil apigenin and taxifolin against SARS-CoV-2 RNA-dependent RNA polymerase (RdRP): In silico, pharmacokinetic, ADMET, and in-vitro approaches
Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis
Design, synthesis, and biological evaluation of indole-2-carboxamides as SARS CoV-2 main protease inhibitors
Design, Synthesis, and Biological Evaluation of New Indole-2-Carboxamides as Anti-Coronaviral Agents Targeting SARS CoV-2 Main Protease inhibitors
Introducing of novel class of pyrano[2,3-c]pyrazole-5- carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation
Pioglitazone ameliorates cisplatin-induced testicular toxicity by attenuating oxidative stress and inflammation via TLR4/MyD88/NF-κB signaling pathway
Design, synthesis, docking and mechanistic studies of new thiazolyl/thiazolidinylpyrimidine-2,4-dione antiproliferative agents
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities
Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
Alginate-chitosan-microencapsulated tyrosols/oleuropein-rich olive mill waste extract for lipopolysaccharide-induced skin fibroblast inflammation treatment
Design, synthesis and antimicrobial activity of novel quinoline- 2-one hybrids as promising DNA gyrase and topoisomerase IV inhibitors
Development of Olive Oil Containing Phytosomal Nanocomplex for Improving Skin Delivery of Quercetin: Formulation Design Optimization, In Vitro and Ex Vivo Appraisals
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities
Polysaccharide-Based Hydrogel from Seeds of Artemisia vulgaris: Extraction Optimization by Box–Behnken Design, pH-Responsiveness, and Sustained Drug Release
Design, Synthesis and Biological Evaluation of Syn and Anti-like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action
Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAFV600E
Design, synthesis, docking and mechanistic studies of new thiazolyl/thiazolidinylpyrimidine-2,4-dione antiproliferative agents
Development of Olive Oil Containing Phytosomal Nanocomplex for Improving Skin Delivery of Quercetin: Formulation Design Optimization, In Vitro and Ex Vivo Appraisals
Discovery of new 5-substituted-indole-2- carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities
Exploring the potential of quercetin/aspirin‑loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced‑colorectal cancer in rats
Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges
Synthesis of bis‑thiohydantoin derivatives as an antiproliferative agents targeting EGFR inhibitory pathway
Design, Synthesis, and antiproliferative action of purine/pteridine-based derivatives as dual inhibitors of EGFR and BRAFV600E
Exploring the potential of quercetin/aspirin‐loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced‐colorectal cancer in rats
Discovery of new 5-substituted-indole-2- carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action
Interactive Effect of Arbuscular Mycorrhizal Fungi (AMF) and Olive Solid Waste on Wheat under Arsenite Toxicity
Chalcone/1,3,4-Oxadiazole/Benzimidazole hybrids as novel anti-proliferative agents inducing apoptosis and inhibiting EGFR & BRAFV600E
Positive Interaction of Selenium Nanoparticles and Olive Solid Waste on Vanadium-Stressed Soybean Plant
Revealing the Underlying Mechanism of Acacia Nilotica against Asthma from a Systematic Perspective: A Network Pharmacology and Molecular Docking Study
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations
Chromium(VI) Toxicity and Active Tolerance Mechanisms of Wheat Plant Treated with Plant Growth-Promoting Actinobacteria and Olive Solid Waste
Phenylboronic Acid-Grafted Chitosan Nanocapsules for Effective Delivery and Controllable Release of Natural Antioxidants: Olive Oil and Hydroxytyrosol
Phenylboronic Acid-Grafted Chitosan Nanocapsules for Effective Delivery and Controllable Release of Natural Antioxidants: Olive Oil and Hydroxytyrosol
Nanoparticles in Drug Delivery: From History to Therapeutic Applications
Revealing genetic links of Type 2 diabetes that lead to the development of Alzheimer’s disease
Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications
Polysaccharide-Based Nanomedicines Targeting Lung Cancer
A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases
Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia
Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats
Potential role of nutraceuticals via targeting a Wnt/β-catenin and NF-κB pathway in treatment of osteoarthritis
Barriers and facilitators of childhood COVID-19 vaccination among parents: A systematic review
Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties
New pyrimidine/thiazole hybrids endowed with analgesic, anti‐inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX‐2/sEH dual inhibition
Peripheral mRNA Expression and Prognostic Significance of Emotional Stress Biomarkers in Metastatic Breast Cancer Patients
Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties
Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review
Development and assessment of phospholipid-based luteolin-loaded lipid nanocapsules for skin delivery
Green Tea Catechins Attenuate Neurodegenerative Diseases and Cognitive Deficits
Incidence, risk factors and outcomes of acute kidney injury among COVID-19 patients: A systematic review of systematic reviews
Butin Mitigates Memory Impairment in Streptozotocin-Induced Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Responses
Molecular exploration of hidden pleiotropic activities of azoles on dermatophytes in human tinea corporis infection
Oligonucleotides: A novel area of interest for drug delivery in neurodegenerative diseases
Development of Ciprofloxacin-Loaded Bilosomes In-Situ Gel for Ocular Delivery: Optimization, In-Vitro Characterization, Ex-Vivo Permeation, and Antimicrobial Study
Europinidin Inhibits Rotenone-Activated Parkinson’s Disease in Rodents by Decreasing Lipid Peroxidation and Inflammatory Cytokines Pathways
Bioanalytical Method Development, Validation and Stability Assessment of Xanthohumol in Rat Plasma
mTOR as a Potential Target for the Treatment of Microbial Infections, Inflammatory Bowel Diseases, and Colorectal Cancer
A comprehensive review of recent advances in the biological activities of quinazolines
New 1,3,4‐oxadiazole‐chalcone/benzimidazole hybrids as potent antiproliferative agents
Effects of the Anthocyanin Hirsutidin on Gastric Ulcers: Improved Healing through Antioxidant Mechanisms
An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy
42- Design and synthesis of new triarylimidazole derivatives as dual inhibitors of BRAFV600E/p38α with potential antiproliferative activity
Design, synthesis, crystal structures and biological evaluation of some 1,3-thiazolidin-4-ones as dual CDK2/EGFR potent inhibitors with potential apoptotic antiproliferative effects
Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities
Sodium alginate based drug delivery in management of breast cancer
43- Structure-based design, synthesis and antiproliferative action of new quizoline-4-one/chalcone hybrids as EGFR inhibitors
Development and assessment of phospholipid-based luteolin- loaded lipid nanocapsules for skin delivery
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties
Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF- Signaling Pathways
Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF-α Signaling Pathways
New 1,3,4‐oxadiazole‐chalcone/benzimidazole hybrids as potent antiproliferative agents
A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction
The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation
Identification and construction of a multi‐epitopes vaccine design against Klebsiella aerogenes: molecular modeling study
46- Discovery of new pyrimido [5,4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies
48- New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX/2/sEH dual inhibition
50- Novel indazole derivatives as potent apoptotic antiproliferative agents by multi-targeted mechanism: Synthesis and biological evaluation
Design, Synthesis, and Antiproliferative Activity of Quinazolin-4-One/Chalcone Hybrids Via the Egfr Inhibition Pathway
Anti-Hypertensive Activity of Some Selected Unani Formulations: An Evidence-Based Approach for Verification of Traditional Unani Claims Using LC-MS/MS for the Evaluation of Clinically Relevant Blood Parameters in Laboratory Rats
Mechanistic study of the antibacterial potential of the prenylated flavonoid auriculasin against Escherichia coli
Rosinidin Protects against Cisplatin-Induced Nephrotoxicity via Subsiding Proinflammatory and Oxidative Stress Biomarkers in Rats
Network Pharmacology and Molecular Docking Based Prediction of Mechanism of Pharmacological Attributes of Glutinol
Anti-Huntington’s Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
Anti-Huntington’s Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
The Ameliorative Role of Hibiscetin against High-Fat Diets and Streptozotocin-Induced Diabetes in Rodents via Inhibiting Tumor Necrosis Factor-α, Interleukin-1β, and Malondialdehyde Level
45- New 1,3,4-oxadiazoles linked with the 1,2,3-triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase
52- Mechanistic study of the antibacterial potential of the prenylated flavonoid auriculasin against Escherichia coli
A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment
Antiamnesic Potential of Malvidin on Aluminum Chloride Activated by the Free Radical Scavenging Property
DOI: https://doi.org/10.1021/acsomega.2c01406?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as
Protective Effect of Fustin Against Ethanol-Activated Gastric Ulcer via Downregulation of Biochemical Parameters in Rats
DOI: https://doi.org/10.1021/acsomega.2c01341?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as
Surveillance of Post-Vaccination Side Effects of COVID-19 Vaccines among Saudi Population: A Real-World Estimation of Safety Profile
Mechanisms underlying the hepatoprotective effect of silymarin on fluoxetine‑induced liver injury in rats: the implication of peroxisome proliferator–activated receptor‑gamma (PPAR‑γ)
Anti-Huntington’s Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action
Current Overview on Therapeutic Potential of Vitamin D in Inflammatory Lung Diseases
Fustin Inhibits Oxidative Free Radicals and Inflammatory Cytokines in Cerebral Cortex and Hippocampus and Protects Cognitive Impairment in Streptozotocin-Induced Diabetic Rats
Polycystic Ovarian Syndrome: A Complex Disease with a Genetics Approach
Role of platelet rich plasma mediated repair and regeneration of cell in early stage of cardiac injury
Sodium-Glucose Cotransporter-2 Inhibitors Improve Cardiovascular Dysfunction in Type 2 Diabetic East Asians
Novel indazole derivatives as potent apoptotic antiproliferative agents by multi-targeted mechanism: Synthesis and biological evaluation
49- In Vitro Anti-Proliferative, and Kinase Inhibitory Activity of Phenanthroindolizidine Alkaloids Isolated from Tylophora indica
In Vitro Anti-Proliferative, and Kinase Inhibitory Activity of Phenanthroindolizidine Alkaloids Isolated fromTylophora indica
Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre / Pro-biotics in manipulating microflora
Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF‑κB and upregulating PPAR‑γ signal
New 1,2,4‐oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives asEGFRandBRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities
In Vivo Assessment of the Ameliorative Impact of Some Medicinal Plant Extracts on Lipopolysaccharide-Induced Multiple Sclerosis in Wistar Rats
Rosinidin Flavonoid Ameliorates Hyperglycemia, Lipid Pathways and Proinflammatory Cytokines in Streptozotocin-Induced Diabetic Rats
Polycystic Ovarian Syndrome: A Complex Disease with a Genetics Approach
Development of[(2E,6E)-2,6-bis (4- (Dimethylamino) benzylidene) cyclohexanone] as fluorescence-on probe for Hg2+ ion detection: computational aided Experimental Studies
Discovery of new pyrimido[5,4-c]quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies
Butin Attenuates Arthritis in Complete Freund’s Adjuvant-Treated Arthritic Rats: Possibly Mediated by Its Antioxidant and Anti-Inflammatory Actions
Bioactive Luteolin Entrapped Chitosan-PLGA Nanoparticles: Formulation Optimization to In-Vivo Preclinical Evaluation
Theranostic Interpolation of Genomic Instability in Breast Cancer
Genes and Longevity of Lifespan
Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a] indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a] indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities
Musa sp. Leaves Extract Ameliorates the Hepato-Renal Toxicities Induced by Cadmium in Mice
Structure-based design, synthesis and antiproliferative action of new quizoline-4-one/chalcone hybrids as EGFR inhibitors
New1,3,4?oxadiazoles linked with the 1,2,3?triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase
Butin attenuates arthritis in Complete Freund's Adjuvant-treated arthritic rats: Possibly mediated by its antioxidant and anti-inflammatory actions
6‐Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/ Depression-like Behavior via Inhibition of Oxidative Stress- Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism
DOI: https://doi.org/10.1021/acsomega.1c04155?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as
The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice
Design and synthesis of new triarylimidazole derivatives as dual inhibitors of BRAF V600E /p38 ?with potential antiproliferative activity
Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study
Green Synthesis and Characterization of Copper Nanoparticles Using Fortunella margarita Leaves
Current Overview on Therapeutic Potential of Vitamin D in Inflammatory Lung Diseases
Nanotechnology as a Novel Approach in Combating Microbes Providing an Alternative to Antibiotics
Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)- 1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents
Novel 1,2,4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease
Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects
Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation
Influence of Stabilizer on the Development of Luteolin Nanosuspension for Cutaneous Delivery: An In Vitro and In Vivo Evaluation
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease
Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease
Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects
Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects
Identification of non-classical hCA XII inhibitors using combination of computational approaches for drug design and discovery
New quinoline/1,2,4-triazole hybrids as dual inhibitors of COX-2/5-LOX and inflammatory cytokines: Design, synthesis, and docking study
Cytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico AnalysisCytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico Analysis
Cytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico Analysis
6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents
Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and bioavailability enhancement
Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity
Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors
Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV
Potential Anticancer Lipoxygenase Inhibitors from the Red Sea-Derived Brown Algae Sargassum cinereum: An In-Silico-Supported In-Vitro Study
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile
Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice
6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents
Holospiniferoside: A New Antitumor Cerebroside from The Red Sea Cucumber Holothuria spinifera: In Vitro and In Silico Studies
Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment
Potential of Natural Bioactive Compounds in Management of Diabetes: Review of Preclinical and Clinical Evidence
Repurposing of FDA Approved Alkaloids as COVID 19 Inhibitors; In Silico Studies
Novel nanotechnology approaches for diagnosis and therapy of breast, ovarian and cervical cancer in female: A review
Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity
Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: synthesis and anticancer activity
Relationship between Pre-Eclampsia, Renal Impairment and Hepatic Insufficiency among Pregnant Women in Al-Jouf Area
An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation
Nanocrystals: Characterization Overview, Applications in Drug Delivery, and Their Toxicity Concerns
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage
Recent updates on novel therapeutic targets of cardiovascular diseases
BBD-Based Development of Itraconazole Loaded Nanostructured Lipid Carrier for Topical Delivery: In Vitro Evaluation and Antimicrobial Assessment
Implications of Solid Lipid Nanoparticles of Ganoderic Acid for the Treatment and Management of Hepatocellular Carcinoma
Role of rivaroxaban in sunitinib?induced renal injuries via inhibition of oxidative stress?induced apoptosis and inflammation through the tissue nacrosis factor?? induced nuclear factor??appa B signaling pathway in rats
Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel
Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice
Genotoxic potential of a Novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice
Combating atherosclerosis with targeted Diosmin nanoparticles- treated experimental diabetes.
Eco-friendly Microwave Synthesis of Gold Nanoparticles for Attenuation of Brain Dysfunction in Diabetic Rats
DOI: https://doi.org/10.1007/s10876-020-01801-y(0123456789().,-vol(V0)123456789().,-volV)
Phytoconstituents and bioactivities of the bark of Pleiogynium timorense (DC.) Leenh (Anacardiaceae)
Bio-Medical Studies (In Vitro) on Psidium guajava Leaves.
5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents
Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones
Fe3O4 nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors
The Effect of Canertinib on Sensitivity of Cytotoxic Drugs in Tamoxifen-Resistant Breast Cancer Cells In Vitro