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DOI: https://doi.org/10.1016/j.bioorg.2022.105616

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Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Bioorganic Chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105616

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives asEGFRandBRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Bioorganic Chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105616

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a] indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Bioorganic Chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105616

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a] indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Bioorganic Chemistry | 2022

DOI: https://doi.org/10.1016/j.bioorg.2022.105616